What is the correct procedure to follow when a mistake is made on a bench sheet?

When a mistake is made on a bench sheet, the appropriate procedure is to mark through the error with a single line, then initial and date it. This method serves multiple purposes in laboratory practice. First, it provides a clear indication of where the error occurred without obscuring the original entry completely. The single line allows the underlying information to remain visible, preserving a record of what was initially written. Additionally, by initialing and dating the correction, it establishes accountability, showing that the correction was acknowledged by the individual who made the error. This practice is important for maintaining the integrity of laboratory records, ensuring that any changes are traceable and that the data remains reliable.

The other options don't align with best practices in documentation. Using a thick line could leave the original entry completely illegible, creating confusion about what the original data was. Simply replacing the sheet eliminates past data, which can compromise record-keeping and auditing processes. Circling the error might not clearly indicate that a mistake was made or provide an adequate resolution, thereby lacking the necessary clarity and accountability found in the preferred method. Proper documentation procedures are crucial in laboratory settings to ensure data integrity and compliance with regulatory standards.